What is e? Math has many important constants, like pi and i, the imaginary number that is equal to the square root of negative one. • E−value Equation The actual equation is E=Kmn(e−λS) The parameters K and λ represent natural scales for the search space and the scoring system respectively. The definition of the E−value is: The probability due to chance, that there is another alignment with a similarity greater than the given S score.

"e" is a numerical constant that is equal to 2.71828. e is an irrational number (it cannot be written as a simple fraction).. e is the base of the Natural Logarithms (invented by John Napier).. e is found in many interesting areas, so is worth learning about.. Calculating. • The E−value is a measure of the reliability of the S score.

Blast results are sorted by E-value by default (best hit in first line). It will always be approximately 2.71828. � E-value can be used as a first quality filter for the BLAST search result, to obtain only results equal to or better than the number given by the -evalue option. There are many ways of calculating the value of e, but none of them ever give a totally exact answer, because e is irrational and its digits go on forever without repeating.

Indeed, the math behind the calculation of e-values, is defined by each program you use (BLAST, HMMer, etc). blastn -query genes.ffn -subject genome.fna -evalue 1e-10 The smaller the E-value, the better the match. As a mathematical constant, the number e remains the same value no matter what math you do to it. Just as pi (3.14159) is a numerical constant that occurs whenever the circumference of a circle is divided by its diameter.

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